Journal of Dental Implant Research 2020; 39(2): 17-23  
Long-term evaluation of autogenous demineralized dentin matrix: A retrospective 7-year clinical study
Yonsoo Shin1, Young-Kyun Kim1,2, In-Woong Um3
1Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam, 2Department of Dentistry & Dental Research Institute, School of Dentistry, Seoul National University,3R&D Institute, Korea Tooth Bank, Seoul, Korea
Correspondence to: Young-Kyun Kim, Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, 82 Gumi-ro, 173beon-gil, Bundang-gu, Seongnam 13620, Korea. Tel: +82-31-787-7541 Fax: +82-31-787-4068 E-mail: kyk0505@snubh.org
Received: March 3, 2020; Revised: March 14, 2020; Accepted: March 16, 2020; Published online: June 30, 2020.
© The Korean Academy of Implant Dentistry. All rights reserved.

This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creative commons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Purpose: Autogenous demineralized dentin matrix (ADDM), derived from human extracted tooth, is commonly used as a bone-graft substitute to reconstruct alveolar defects when placing dental implants. The purpose of this retrospective study is to examine efficacy of ADDM in terms of surgical complications and marginal bone resorption by analyzing the medical records and radiographs of patients.
Materials and Methods: ADDM graft from 2008 to 2011 in our institute. Occurrence of complications, marginal bone loss around implants were investigated with regard to the type of defect, location of bone grafting, and types of bone graft techniques.
Results: ADDM-based bone grafting was performed on 221 sites in 82 patients and 208 implants were placed afterwards: The percentage of complications after bone grafting was 15.84%, and the implant survival rate was 95.19%. All complications were resolved with conventional treatment except for the 10 cases of osseointegration failure. The average marginal bone loss was 0.31 mm at the last examination after the average follow-up period of 7.2 years.
Conclusions: Within the limitation of this study, the results of long-term follow-up are consistent with the short-term results of relevant studies. ADDM can produce promising clinical outcomes when used for alveolar ridge augmentation around implants.
Keywords: Demineralized dentin, Osseointegration, Dental implants


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