Journal of Dental Implant Research 2019; 38(1): 24-29  
Moldable autogenous tooth bone graft (M-AutoBT) in sinus-related defects with implant: 3 case reports of long-term follow up
Jeong-Kui Ku1, Jeong-Keun Lee2, Chul-Gi Min3, Yu-Mi Kim4, In-Woong Um4
1Department of Oral and Maxillofacial Surgery, Section of Dentistry, Armed Forces Capital Hospital, Seongnam, 2Department of Oral and Maxillofacial Surgery, Medical Center, Ajou University, Suwon, 3Seoul Highan Dental Clinic, Seoul, 4R&D Institute, Korea Tooth Bank, Seoul, Korea
Correspondence to: In-Woong Um, R&D Institute, Korea Tooth Bank, 56 Pyeongchangmunhwa-ro, Chongno-gu, Seoul 03011, Korea. Tel: +82-2-395-5522, Fax: +82-2-395-0222, E-mail: h-bmp@daum.net

Jeong-Kui Ku, Department of Oral and Maxillofacial Surgery, Section of Dentistry, Armed Forces Capital Hospital, 117-81 Saemaeul-ro, Bundang-gu, Seongnam 13574, Korea. Tel: +82-31-725-6184, Fax: +82-31-706-0987, E-mail: kujk123@gmail.com
Received: January 15, 2019; Revised: May 12, 2019; Accepted: May 18, 2019; Published online: June 30, 2019.
© The Korean Academy of Implant Dentistry. All rights reserved.

This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creative commons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Purpose: A moldable autogenous tooth bone graft material (M-AutoBT, Korea Tooth Bank, Seoul, Korea), which is made from demineralized dentin matrix (DDM) powder and hydroxypropylmethyl cellulose (HPMC), is sticky and moldable, making it easy to handle and allowing it to fit into large defects. This case report evaluates the remodeling capacity and long-term stability of moldable demineralized dentin matrix (M-AutoBT) in three sinus-related cases first reported in 2015.
Materials and Methods: M-AutoBT, which is made from demineralized dentin matrix (DDM) powder and hydroxypropylmethyl cellulose (HPMC), is a sticky and moldable to fit easily into large defects. Cone-beam computerized tomography was used to evaluate the changes in M-AutoBT around the dental implant in the sinus area from immediately after surgery to the final follow-up (2, 3, and 5 years).
Results: In all three cases, regardless of the sinus graft procedure, M-AutoBT showed successful bone formation around the dental implant and maintained its volume and the shape of the cortico-cancellous bone without marginal bone loss during long-term prosthetic loading.
Conclusions: HPMC is a base material that contains AutoBT powders and is a moldable and injectable bone substitute material (M-AutoBT) that can fit into a range of defects. M-AutoBT has osteoinductive and osteoconductive capacities. The present study suggests that bone-forming capacity and long term stability of M-AutoBT are similar to the conventional AutoBT, regardless of the characteristics of the defect and the different pathways of the blood supply. Therefore, HPMC powder might be an effective base material for conventional AutoBT powder.
Keywords: Bone, Dentin, Bone substitute, Demineralized dentin matrix (DDM)


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